Antidepressants and weight gain: New study reveals winners and losers

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Deep analysis: Relationship between types of antidepressants and weight gain

Depression is a common mental illness that affects the lives of millions around the world. Antidepressants play a vital role in treating this disease, but they are also associated with some side effects, most notably weight gain. In recent years, interest in studying the relationship between different types of antidepressants and their effect on weight has increased. In this article, we will detail the results of recent studies looking at this relationship, and we will provide a comprehensive look at the winners and losers in this battle against overweight.

Mechanisms linking antidepressants to weight gain

There are several mechanisms that may explain the relationship between antidepressants and weight gain, including:

  • Effect on hormones: Some antidepressants may affect levels of hormones such as serotonin and dopamine, which play an important role in regulating appetite and weight.
  • Effect on insulin receptors: Some of these medications may affect the body’s sensitivity to insulin, leading to increased fat storage.
  • Increased appetite: Some people who take antidepressants complain of an increase in appetite, which leads them to eat larger amounts of food.
  • Changes in metabolic rate: Some antidepressants may affect the body’s metabolic rate, resulting in less calorie burning.

Recent studies: Who are the winners and losers?

Several studies have shown that some types of antidepressants are associated with greater weight gain than others. In general, antidepressants can be divided into several categories, and each category has a different effect on weight:

  • Selective serotonin reuptake inhibitors (SSRIs): This class is one of the most common antidepressants and is associated with a slight weight gain in some people.
  • Noradrenaline and serotonin reuptake inhibitors (SNRIs): This class may cause greater weight gain compared to SSRIs.
  • Monoamine oxidase inhibitors (MAOIs): This category may lead to significant weight gain.
  • Tricyclic antidepressants: This category is associated with significant weight gain.
  • Atopic antidepressants: This category is considered one of the most recent types of antidepressants, and is less associated with weight gain compared to other groups.

Other factors affecting weight gain

In addition to the type of antidepressant, there are other factors that may contribute to weight gain during treatment, such as:

  • Dosage: A high dose of antidepressant may be more associated with weight gain.
  • Duration of treatment: The risk of weight gain may increase with the length of treatment.
  • Age and gender: Older people and women may be more likely to gain weight during treatment.
  • Lifestyle: Unhealthy diet and lack of physical activity may increase the risk of weight gain.

How to deal with weight gain during treatment

If you are overweight while taking antidepressants, it is important to consult your doctor. Your doctor may recommend changing the type of medication or adjusting the dose, or may suggest a healthy diet and regular exercise.

The relationship between antidepressants and weight gain is a complex and multifaceted topic. Although some antidepressants may cause weight gain, there are other treatment options that are less associated with these side effects. It’s important to talk to your doctor about the potential risks and benefits of each type of antidepressant, and to determine the most appropriate option for your individual health condition.

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